1 | Seq-entry ::= set { |
---|
2 | level 1 , |
---|
3 | class nuc-prot , |
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4 | descr { |
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5 | source { |
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6 | genome genomic , |
---|
7 | org { |
---|
8 | taxname "Homo sapiens" , |
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9 | common "human" , |
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10 | db { |
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11 | { |
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12 | db "taxon" , |
---|
13 | tag |
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14 | id 9606 } } , |
---|
15 | orgname { |
---|
16 | name |
---|
17 | binomial { |
---|
18 | genus "Homo" , |
---|
19 | species "sapiens" } , |
---|
20 | lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; |
---|
21 | Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; |
---|
22 | Catarrhini; Hominidae; Homo" , |
---|
23 | gcode 1 , |
---|
24 | mgcode 2 , |
---|
25 | div "PRI" } } , |
---|
26 | subtype { |
---|
27 | { |
---|
28 | subtype chromosome , |
---|
29 | name "3" } , |
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30 | { |
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31 | subtype map , |
---|
32 | name "3p21" } } } , |
---|
33 | comment "~Summary: Dystroglycan is a laminin binding component of the |
---|
34 | dystrophin-glycoprotein complex which provides a linkage between the |
---|
35 | subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a |
---|
36 | candidate gene for the site of the mutation in autosomal recessive muscular |
---|
37 | dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular |
---|
38 | dystrophy leads to a loss of linkage between the sarcolemma and extracellular |
---|
39 | matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan |
---|
40 | also functions as dual receptor for agrin and laminin-2 in the Schwann cell |
---|
41 | membrane. The muscle and nonmuscle isoforms of dystroglycan differ by |
---|
42 | carbohydrate moieties but not protein sequence." , |
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43 | user { |
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44 | type |
---|
45 | str "RefGeneTracking" , |
---|
46 | data { |
---|
47 | { |
---|
48 | label |
---|
49 | str "Status" , |
---|
50 | data |
---|
51 | str "Reviewed" } , |
---|
52 | { |
---|
53 | label |
---|
54 | str "Assembly" , |
---|
55 | data |
---|
56 | fields { |
---|
57 | { |
---|
58 | label |
---|
59 | id 0 , |
---|
60 | data |
---|
61 | fields { |
---|
62 | { |
---|
63 | label |
---|
64 | str "accession" , |
---|
65 | data |
---|
66 | str "DA851197.1" } } } , |
---|
67 | { |
---|
68 | label |
---|
69 | id 0 , |
---|
70 | data |
---|
71 | fields { |
---|
72 | { |
---|
73 | label |
---|
74 | str "accession" , |
---|
75 | data |
---|
76 | str "BC012740.2" } , |
---|
77 | { |
---|
78 | label |
---|
79 | str "gi" , |
---|
80 | data |
---|
81 | int 15215308 } } } , |
---|
82 | { |
---|
83 | label |
---|
84 | id 0 , |
---|
85 | data |
---|
86 | fields { |
---|
87 | { |
---|
88 | label |
---|
89 | str "accession" , |
---|
90 | data |
---|
91 | str "L19711.1" } , |
---|
92 | { |
---|
93 | label |
---|
94 | str "gi" , |
---|
95 | data |
---|
96 | int 398026 } } } , |
---|
97 | { |
---|
98 | label |
---|
99 | id 0 , |
---|
100 | data |
---|
101 | fields { |
---|
102 | { |
---|
103 | label |
---|
104 | str "accession" , |
---|
105 | data |
---|
106 | str "CX871468.1" } } } , |
---|
107 | { |
---|
108 | label |
---|
109 | id 0 , |
---|
110 | data |
---|
111 | fields { |
---|
112 | { |
---|
113 | label |
---|
114 | str "accession" , |
---|
115 | data |
---|
116 | str "BX402174.2" } } } , |
---|
117 | { |
---|
118 | label |
---|
119 | id 0 , |
---|
120 | data |
---|
121 | fields { |
---|
122 | { |
---|
123 | label |
---|
124 | str "accession" , |
---|
125 | data |
---|
126 | str "BF476692.1" } } } , |
---|
127 | { |
---|
128 | label |
---|
129 | id 0 , |
---|
130 | data |
---|
131 | fields { |
---|
132 | { |
---|
133 | label |
---|
134 | str "accession" , |
---|
135 | data |
---|
136 | str "AW204012.1" } } } } } } } , |
---|
137 | comment "~Publication Note: This RefSeq record includes a subset of the |
---|
138 | publications that are available for this gene. Please see the Entrez Gene |
---|
139 | record to access additional publications." , |
---|
140 | pub { |
---|
141 | pub { |
---|
142 | pmid 17640712 , |
---|
143 | article { |
---|
144 | title { |
---|
145 | name "Altered expression of natively glycosylated alpha |
---|
146 | dystroglycan in pediatric solid tumors." } , |
---|
147 | authors { |
---|
148 | names |
---|
149 | std { |
---|
150 | { |
---|
151 | name |
---|
152 | name { |
---|
153 | last "Martin" , |
---|
154 | initials "L.T." } } , |
---|
155 | { |
---|
156 | name |
---|
157 | name { |
---|
158 | last "Glass" , |
---|
159 | initials "M." } } , |
---|
160 | { |
---|
161 | name |
---|
162 | name { |
---|
163 | last "Dosunmu" , |
---|
164 | initials "E." } } , |
---|
165 | { |
---|
166 | name |
---|
167 | name { |
---|
168 | last "Martin" , |
---|
169 | initials "P.T." } } } , |
---|
170 | affil |
---|
171 | str "Division of Pediatric Hematology/Oncology, Department of |
---|
172 | Pediatrics, Ohio State University College of Medicine and Public Health, |
---|
173 | Columbus, OH 43205, USA. martinlt@pediatrics.ohio-state.edu" } , |
---|
174 | from |
---|
175 | journal { |
---|
176 | title { |
---|
177 | iso-jta "Hum. Pathol." , |
---|
178 | ml-jta "Hum Pathol" , |
---|
179 | issn "0046-8177" , |
---|
180 | name "Human pathology" } , |
---|
181 | imp { |
---|
182 | date |
---|
183 | std { |
---|
184 | year 2007 , |
---|
185 | month 11 } , |
---|
186 | volume "38" , |
---|
187 | issue "11" , |
---|
188 | pages "1657-1668" , |
---|
189 | language "eng" , |
---|
190 | pubstatus ppublish , |
---|
191 | history { |
---|
192 | { |
---|
193 | pubstatus received , |
---|
194 | date |
---|
195 | std { |
---|
196 | year 2006 , |
---|
197 | month 7 , |
---|
198 | day 10 } } , |
---|
199 | { |
---|
200 | pubstatus revised , |
---|
201 | date |
---|
202 | std { |
---|
203 | year 2006 , |
---|
204 | month 11 , |
---|
205 | day 28 } } , |
---|
206 | { |
---|
207 | pubstatus accepted , |
---|
208 | date |
---|
209 | std { |
---|
210 | year 2007 , |
---|
211 | month 3 , |
---|
212 | day 12 } } , |
---|
213 | { |
---|
214 | pubstatus aheadofprint , |
---|
215 | date |
---|
216 | std { |
---|
217 | year 2007 , |
---|
218 | month 7 , |
---|
219 | day 19 } } , |
---|
220 | { |
---|
221 | pubstatus pubmed , |
---|
222 | date |
---|
223 | std { |
---|
224 | year 2007 , |
---|
225 | month 7 , |
---|
226 | day 21 , |
---|
227 | hour 9 , |
---|
228 | minute 0 } } , |
---|
229 | { |
---|
230 | pubstatus medline , |
---|
231 | date |
---|
232 | std { |
---|
233 | year 2007 , |
---|
234 | month 12 , |
---|
235 | day 21 , |
---|
236 | hour 9 , |
---|
237 | minute 0 } } } } } , |
---|
238 | ids { |
---|
239 | pii "S0046-8177(07)00162-1" , |
---|
240 | doi "10.1016/j.humpath.2007.03.025" , |
---|
241 | pubmed 17640712 } } } , |
---|
242 | comment "GeneRIF: alpha dystroglycan glycosylation & laminin binding to |
---|
243 | alpha dystroglycan are altered in certain pediatric solid tumors and suggest |
---|
244 | that aberrant dystroglycan glycosylation may contribute to tumor cell biology |
---|
245 | in patients with RMS, medulloblastoma, & NBL." } , |
---|
246 | pub { |
---|
247 | pub { |
---|
248 | pmid 17516554 , |
---|
249 | article { |
---|
250 | title { |
---|
251 | name "Dystroglycan expression is reduced during prostate |
---|
252 | tumorigenesis and is regulated by androgens in prostate cancer cells." } , |
---|
253 | authors { |
---|
254 | names |
---|
255 | std { |
---|
256 | { |
---|
257 | name |
---|
258 | name { |
---|
259 | last "Sgambato" , |
---|
260 | initials "A." } } , |
---|
261 | { |
---|
262 | name |
---|
263 | name { |
---|
264 | last "De Paola" , |
---|
265 | initials "B." } } , |
---|
266 | { |
---|
267 | name |
---|
268 | name { |
---|
269 | last "Migaldi" , |
---|
270 | initials "M." } } , |
---|
271 | { |
---|
272 | name |
---|
273 | name { |
---|
274 | last "Di Salvatore" , |
---|
275 | initials "M." } } , |
---|
276 | { |
---|
277 | name |
---|
278 | name { |
---|
279 | last "Rettino" , |
---|
280 | initials "A." } } , |
---|
281 | { |
---|
282 | name |
---|
283 | name { |
---|
284 | last "Rossi" , |
---|
285 | initials "G." } } , |
---|
286 | { |
---|
287 | name |
---|
288 | name { |
---|
289 | last "Faraglia" , |
---|
290 | initials "B." } } , |
---|
291 | { |
---|
292 | name |
---|
293 | name { |
---|
294 | last "Boninsegna" , |
---|
295 | initials "A." } } , |
---|
296 | { |
---|
297 | name |
---|
298 | name { |
---|
299 | last "Maiorana" , |
---|
300 | initials "A." } } , |
---|
301 | { |
---|
302 | name |
---|
303 | name { |
---|
304 | last "Cittadini" , |
---|
305 | initials "A." } } } , |
---|
306 | affil |
---|
307 | str "Laboratorio di Oncologia Molecolare, Centro di Riferimento |
---|
308 | Oncologico di Basilicata, Rionero in Vulture (PZ), Italy. |
---|
309 | asgambato@rm.unicatt.it" } , |
---|
310 | from |
---|
311 | journal { |
---|
312 | title { |
---|
313 | iso-jta "J. Cell. Physiol." , |
---|
314 | ml-jta "J Cell Physiol" , |
---|
315 | issn "0021-9541" , |
---|
316 | name "Journal of cellular physiology" } , |
---|
317 | imp { |
---|
318 | date |
---|
319 | std { |
---|
320 | year 2007 , |
---|
321 | month 11 } , |
---|
322 | volume "213" , |
---|
323 | issue "2" , |
---|
324 | pages "528-539" , |
---|
325 | language "eng" , |
---|
326 | pubstatus ppublish , |
---|
327 | history { |
---|
328 | { |
---|
329 | pubstatus pubmed , |
---|
330 | date |
---|
331 | std { |
---|
332 | year 2007 , |
---|
333 | month 5 , |
---|
334 | day 23 , |
---|
335 | hour 9 , |
---|
336 | minute 0 } } , |
---|
337 | { |
---|
338 | pubstatus medline , |
---|
339 | date |
---|
340 | std { |
---|
341 | year 2008 , |
---|
342 | month 1 , |
---|
343 | day 23 , |
---|
344 | hour 9 , |
---|
345 | minute 0 } } } } } , |
---|
346 | ids { |
---|
347 | doi "10.1002/jcp.21130" , |
---|
348 | pubmed 17516554 } } } , |
---|
349 | comment "GeneRIF: Data suggest that disturbances in the function of the |
---|
350 | dystroglycan complex might contribute to the definition of the malignant |
---|
351 | behavior of prostate cancer cells and suggest that androgens might regulate |
---|
352 | DG expression in these cells." } , |
---|
353 | pub { |
---|
354 | pub { |
---|
355 | pmid 17012237 , |
---|
356 | article { |
---|
357 | title { |
---|
358 | name "Activation of muscle-specific receptor tyrosine kinase and |
---|
359 | binding to dystroglycan are regulated by alternative mRNA splicing of agrin." } , |
---|
360 | authors { |
---|
361 | names |
---|
362 | std { |
---|
363 | { |
---|
364 | name |
---|
365 | name { |
---|
366 | last "Scotton" , |
---|
367 | initials "P." } } , |
---|
368 | { |
---|
369 | name |
---|
370 | name { |
---|
371 | last "Bleckmann" , |
---|
372 | initials "D." } } , |
---|
373 | { |
---|
374 | name |
---|
375 | name { |
---|
376 | last "Stebler" , |
---|
377 | initials "M." } } , |
---|
378 | { |
---|
379 | name |
---|
380 | name { |
---|
381 | last "Sciandra" , |
---|
382 | initials "F." } } , |
---|
383 | { |
---|
384 | name |
---|
385 | name { |
---|
386 | last "Brancaccio" , |
---|
387 | initials "A." } } , |
---|
388 | { |
---|
389 | name |
---|
390 | name { |
---|
391 | last "Meier" , |
---|
392 | initials "T." } } , |
---|
393 | { |
---|
394 | name |
---|
395 | name { |
---|
396 | last "Stetefeld" , |
---|
397 | initials "J." } } , |
---|
398 | { |
---|
399 | name |
---|
400 | name { |
---|
401 | last "Ruegg" , |
---|
402 | initials "M.A." } } } , |
---|
403 | affil |
---|
404 | str "Biozentrum, University of Basel, Klingelbergstrasse 70, |
---|
405 | CH-4056 Basel, Switzerland." } , |
---|
406 | from |
---|
407 | journal { |
---|
408 | title { |
---|
409 | iso-jta "J. Biol. Chem." , |
---|
410 | ml-jta "J Biol Chem" , |
---|
411 | issn "0021-9258" , |
---|
412 | name "The Journal of biological chemistry" } , |
---|
413 | imp { |
---|
414 | date |
---|
415 | std { |
---|
416 | year 2006 , |
---|
417 | month 12 , |
---|
418 | day 1 } , |
---|
419 | volume "281" , |
---|
420 | issue "48" , |
---|
421 | pages "36835-36845" , |
---|
422 | language "eng" , |
---|
423 | pubstatus ppublish , |
---|
424 | history { |
---|
425 | { |
---|
426 | pubstatus aheadofprint , |
---|
427 | date |
---|
428 | std { |
---|
429 | year 2006 , |
---|
430 | month 9 , |
---|
431 | day 29 } } , |
---|
432 | { |
---|
433 | pubstatus pubmed , |
---|
434 | date |
---|
435 | std { |
---|
436 | year 2006 , |
---|
437 | month 10 , |
---|
438 | day 3 , |
---|
439 | hour 9 , |
---|
440 | minute 0 } } , |
---|
441 | { |
---|
442 | pubstatus medline , |
---|
443 | date |
---|
444 | std { |
---|
445 | year 2007 , |
---|
446 | month 1 , |
---|
447 | day 31 , |
---|
448 | hour 9 , |
---|
449 | minute 0 } } } } } , |
---|
450 | ids { |
---|
451 | pii "M607887200" , |
---|
452 | doi "10.1074/jbc.M607887200" , |
---|
453 | pubmed 17012237 } } } , |
---|
454 | comment "GeneRIF: muscle-specific receptor tyrosine kinase activation |
---|
455 | and binding to dystroglycan are regulated by alternative mRNA splicing of |
---|
456 | agrin" } , |
---|
457 | pub { |
---|
458 | pub { |
---|
459 | pmid 17005282 , |
---|
460 | article { |
---|
461 | title { |
---|
462 | name "Intracellular binding of fukutin and alpha-dystroglycan: |
---|
463 | relation to glycosylation of alpha-dystroglycan." } , |
---|
464 | authors { |
---|
465 | names |
---|
466 | std { |
---|
467 | { |
---|
468 | name |
---|
469 | name { |
---|
470 | last "Yamamoto" , |
---|
471 | initials "T." } } , |
---|
472 | { |
---|
473 | name |
---|
474 | name { |
---|
475 | last "Kawaguchi" , |
---|
476 | initials "M." } } , |
---|
477 | { |
---|
478 | name |
---|
479 | name { |
---|
480 | last "Sakayori" , |
---|
481 | initials "N." } } , |
---|
482 | { |
---|
483 | name |
---|
484 | name { |
---|
485 | last "Muramatsu" , |
---|
486 | initials "F." } } , |
---|
487 | { |
---|
488 | name |
---|
489 | name { |
---|
490 | last "Morikawa" , |
---|
491 | initials "S." } } , |
---|
492 | { |
---|
493 | name |
---|
494 | name { |
---|
495 | last "Kato" , |
---|
496 | initials "Y." } } , |
---|
497 | { |
---|
498 | name |
---|
499 | name { |
---|
500 | last "Shibata" , |
---|
501 | initials "N." } } , |
---|
502 | { |
---|
503 | name |
---|
504 | name { |
---|
505 | last "Kobayashi" , |
---|
506 | initials "M." } } } , |
---|
507 | affil |
---|
508 | str "Department of Pathology, Tokyo Women's Medical University, |
---|
509 | Tokyo, Japan. sheto@research.twmu.ac.jp" } , |
---|
510 | from |
---|
511 | journal { |
---|
512 | title { |
---|
513 | iso-jta "Neurosci. Res." , |
---|
514 | ml-jta "Neurosci Res" , |
---|
515 | issn "0168-0102" , |
---|
516 | name "Neuroscience research" } , |
---|
517 | imp { |
---|
518 | date |
---|
519 | std { |
---|
520 | year 2006 , |
---|
521 | month 12 } , |
---|
522 | volume "56" , |
---|
523 | issue "4" , |
---|
524 | pages "391-399" , |
---|
525 | language "eng" , |
---|
526 | pubstatus ppublish , |
---|
527 | history { |
---|
528 | { |
---|
529 | pubstatus received , |
---|
530 | date |
---|
531 | std { |
---|
532 | year 2006 , |
---|
533 | month 1 , |
---|
534 | day 21 } } , |
---|
535 | { |
---|
536 | pubstatus revised , |
---|
537 | date |
---|
538 | std { |
---|
539 | year 2006 , |
---|
540 | month 8 , |
---|
541 | day 14 } } , |
---|
542 | { |
---|
543 | pubstatus accepted , |
---|
544 | date |
---|
545 | std { |
---|
546 | year 2006 , |
---|
547 | month 8 , |
---|
548 | day 17 } } , |
---|
549 | { |
---|
550 | pubstatus aheadofprint , |
---|
551 | date |
---|
552 | std { |
---|
553 | year 2006 , |
---|
554 | month 9 , |
---|
555 | day 26 } } , |
---|
556 | { |
---|
557 | pubstatus pubmed , |
---|
558 | date |
---|
559 | std { |
---|
560 | year 2006 , |
---|
561 | month 9 , |
---|
562 | day 29 , |
---|
563 | hour 9 , |
---|
564 | minute 0 } } , |
---|
565 | { |
---|
566 | pubstatus medline , |
---|
567 | date |
---|
568 | std { |
---|
569 | year 2007 , |
---|
570 | month 1 , |
---|
571 | day 18 , |
---|
572 | hour 9 , |
---|
573 | minute 0 } } } } } , |
---|
574 | ids { |
---|
575 | pii "S0168-0102(06)00215-X" , |
---|
576 | doi "10.1016/j.neures.2006.08.009" , |
---|
577 | pubmed 17005282 } } } , |
---|
578 | comment "GeneRIF: Fukutin seems to bind to both the hypoglycosylated and |
---|
579 | fully glycosylated form of alpha-dystroglycan, and seems bind to the core |
---|
580 | area rather than the sugar chain of alpha-dystroglycan" } , |
---|
581 | pub { |
---|
582 | pub { |
---|
583 | pmid 16709410 , |
---|
584 | article { |
---|
585 | title { |
---|
586 | name "Brain alpha-dystroglycan displays unique glycoepitopes and |
---|
587 | preferential binding to laminin-10/11." } , |
---|
588 | authors { |
---|
589 | names |
---|
590 | std { |
---|
591 | { |
---|
592 | name |
---|
593 | name { |
---|
594 | last "McDearmon" , |
---|
595 | initials "E.L." } } , |
---|
596 | { |
---|
597 | name |
---|
598 | name { |
---|
599 | last "Combs" , |
---|
600 | initials "A.C." } } , |
---|
601 | { |
---|
602 | name |
---|
603 | name { |
---|
604 | last "Sekiguchi" , |
---|
605 | initials "K." } } , |
---|
606 | { |
---|
607 | name |
---|
608 | name { |
---|
609 | last "Fujiwara" , |
---|
610 | initials "H." } } , |
---|
611 | { |
---|
612 | name |
---|
613 | name { |
---|
614 | last "Ervasti" , |
---|
615 | initials "J.M." } } } , |
---|
616 | affil |
---|
617 | str "Department of Physiology, University of Wisconsin, Madison, |
---|
618 | 53706, USA." } , |
---|
619 | from |
---|
620 | journal { |
---|
621 | title { |
---|
622 | iso-jta "FEBS Lett." , |
---|
623 | ml-jta "FEBS Lett" , |
---|
624 | issn "0014-5793" , |
---|
625 | name "FEBS letters" } , |
---|
626 | imp { |
---|
627 | date |
---|
628 | std { |
---|
629 | year 2006 , |
---|
630 | month 6 , |
---|
631 | day 12 } , |
---|
632 | volume "580" , |
---|
633 | issue "14" , |
---|
634 | pages "3381-3385" , |
---|
635 | language "eng" , |
---|
636 | pubstatus ppublish , |
---|
637 | history { |
---|
638 | { |
---|
639 | pubstatus received , |
---|
640 | date |
---|
641 | std { |
---|
642 | year 2006 , |
---|
643 | month 2 , |
---|
644 | day 14 } } , |
---|
645 | { |
---|
646 | pubstatus revised , |
---|
647 | date |
---|
648 | std { |
---|
649 | year 2006 , |
---|
650 | month 4 , |
---|
651 | day 18 } } , |
---|
652 | { |
---|
653 | pubstatus accepted , |
---|
654 | date |
---|
655 | std { |
---|
656 | year 2006 , |
---|
657 | month 5 , |
---|
658 | day 2 } } , |
---|
659 | { |
---|
660 | pubstatus aheadofprint , |
---|
661 | date |
---|
662 | std { |
---|
663 | year 2006 , |
---|
664 | month 5 , |
---|
665 | day 11 } } , |
---|
666 | { |
---|
667 | pubstatus pubmed , |
---|
668 | date |
---|
669 | std { |
---|
670 | year 2006 , |
---|
671 | month 5 , |
---|
672 | day 20 , |
---|
673 | hour 9 , |
---|
674 | minute 0 } } , |
---|
675 | { |
---|
676 | pubstatus medline , |
---|
677 | date |
---|
678 | std { |
---|
679 | year 2006 , |
---|
680 | month 7 , |
---|
681 | day 28 , |
---|
682 | hour 9 , |
---|
683 | minute 0 } } } } } , |
---|
684 | ids { |
---|
685 | pii "S0014-5793(06)00595-3" , |
---|
686 | doi "10.1016/j.febslet.2006.05.010" , |
---|
687 | pubmed 16709410 } } } } , |
---|
688 | pub { |
---|
689 | pub { |
---|
690 | pmid 7774920 , |
---|
691 | article { |
---|
692 | title { |
---|
693 | name "Genetic mapping of the mouse neuromuscular mutation |
---|
694 | kyphoscoliosis." } , |
---|
695 | authors { |
---|
696 | names |
---|
697 | std { |
---|
698 | { |
---|
699 | name |
---|
700 | name { |
---|
701 | last "Skynner" , |
---|
702 | initials "M.J." } } , |
---|
703 | { |
---|
704 | name |
---|
705 | name { |
---|
706 | last "Gangadharan" , |
---|
707 | initials "U." } } , |
---|
708 | { |
---|
709 | name |
---|
710 | name { |
---|
711 | last "Coulton" , |
---|
712 | initials "G.R." } } , |
---|
713 | { |
---|
714 | name |
---|
715 | name { |
---|
716 | last "Mason" , |
---|
717 | initials "R.M." } } , |
---|
718 | { |
---|
719 | name |
---|
720 | name { |
---|
721 | last "Nikitopoulou" , |
---|
722 | initials "A." } } , |
---|
723 | { |
---|
724 | name |
---|
725 | name { |
---|
726 | last "Brown" , |
---|
727 | initials "S.D." } } , |
---|
728 | { |
---|
729 | name |
---|
730 | name { |
---|
731 | last "Blanco" , |
---|
732 | initials "G." } } } , |
---|
733 | affil |
---|
734 | str "Department of Biochemistry, Charing Cross and Westminster |
---|
735 | Hospital Medical School, London, United Kingdom." } , |
---|
736 | from |
---|
737 | journal { |
---|
738 | title { |
---|
739 | iso-jta "Genomics" , |
---|
740 | ml-jta "Genomics" , |
---|
741 | issn "0888-7543" , |
---|
742 | name "Genomics" } , |
---|
743 | imp { |
---|
744 | date |
---|
745 | std { |
---|
746 | year 1995 , |
---|
747 | month 1 , |
---|
748 | day 1 } , |
---|
749 | volume "25" , |
---|
750 | issue "1" , |
---|
751 | pages "207-213" , |
---|
752 | language "eng" , |
---|
753 | pubstatus ppublish , |
---|
754 | history { |
---|
755 | { |
---|
756 | pubstatus pubmed , |
---|
757 | date |
---|
758 | std { |
---|
759 | year 1995 , |
---|
760 | month 1 , |
---|
761 | day 1 } } , |
---|
762 | { |
---|
763 | pubstatus medline , |
---|
764 | date |
---|
765 | std { |
---|
766 | year 1995 , |
---|
767 | month 1 , |
---|
768 | day 1 , |
---|
769 | hour 0 , |
---|
770 | minute 1 } } } } } , |
---|
771 | ids { |
---|
772 | pubmed 7774920 , |
---|
773 | pii "0888-7543(95)80127-8" } } } } , |
---|
774 | pub { |
---|
775 | pub { |
---|
776 | pmid 7744812 , |
---|
777 | article { |
---|
778 | title { |
---|
779 | name "SH3 domain-mediated interaction of dystroglycan and Grb2." } , |
---|
780 | authors { |
---|
781 | names |
---|
782 | std { |
---|
783 | { |
---|
784 | name |
---|
785 | name { |
---|
786 | last "Yang" , |
---|
787 | initials "B." } } , |
---|
788 | { |
---|
789 | name |
---|
790 | name { |
---|
791 | last "Jung" , |
---|
792 | initials "D." } } , |
---|
793 | { |
---|
794 | name |
---|
795 | name { |
---|
796 | last "Motto" , |
---|
797 | initials "D." } } , |
---|
798 | { |
---|
799 | name |
---|
800 | name { |
---|
801 | last "Meyer" , |
---|
802 | initials "J." } } , |
---|
803 | { |
---|
804 | name |
---|
805 | name { |
---|
806 | last "Koretzky" , |
---|
807 | initials "G." } } , |
---|
808 | { |
---|
809 | name |
---|
810 | name { |
---|
811 | last "Campbell" , |
---|
812 | initials "K.P." } } } , |
---|
813 | affil |
---|
814 | str "Howard Hughes Medical Institute, College of Medicine, Iowa |
---|
815 | City, Iowa, USA." } , |
---|
816 | from |
---|
817 | journal { |
---|
818 | title { |
---|
819 | iso-jta "J. Biol. Chem." , |
---|
820 | ml-jta "J Biol Chem" , |
---|
821 | issn "0021-9258" , |
---|
822 | name "The Journal of biological chemistry" } , |
---|
823 | imp { |
---|
824 | date |
---|
825 | std { |
---|
826 | year 1995 , |
---|
827 | month 5 , |
---|
828 | day 19 } , |
---|
829 | volume "270" , |
---|
830 | issue "20" , |
---|
831 | pages "11711-11714" , |
---|
832 | language "eng" , |
---|
833 | pubstatus ppublish , |
---|
834 | history { |
---|
835 | { |
---|
836 | pubstatus pubmed , |
---|
837 | date |
---|
838 | std { |
---|
839 | year 1995 , |
---|
840 | month 5 , |
---|
841 | day 19 } } , |
---|
842 | { |
---|
843 | pubstatus medline , |
---|
844 | date |
---|
845 | std { |
---|
846 | year 1995 , |
---|
847 | month 5 , |
---|
848 | day 19 , |
---|
849 | hour 0 , |
---|
850 | minute 1 } } } } } , |
---|
851 | ids { |
---|
852 | pubmed 7744812 } } } } , |
---|
853 | pub { |
---|
854 | pub { |
---|
855 | pmid 7619516 , |
---|
856 | article { |
---|
857 | title { |
---|
858 | name "Rapsyn may function as a link between the acetylcholine |
---|
859 | receptor and the agrin-binding dystrophin-associated glycoprotein complex." } , |
---|
860 | authors { |
---|
861 | names |
---|
862 | std { |
---|
863 | { |
---|
864 | name |
---|
865 | name { |
---|
866 | last "Apel" , |
---|
867 | initials "E.D." } } , |
---|
868 | { |
---|
869 | name |
---|
870 | name { |
---|
871 | last "Roberds" , |
---|
872 | initials "S.L." } } , |
---|
873 | { |
---|
874 | name |
---|
875 | name { |
---|
876 | last "Campbell" , |
---|
877 | initials "K.P." } } , |
---|
878 | { |
---|
879 | name |
---|
880 | name { |
---|
881 | last "Merlie" , |
---|
882 | initials "J.P." } } } , |
---|
883 | affil |
---|
884 | str "Department of Molecular Biology and Pharmacology, |
---|
885 | Washington University School of Medicine, St. Louis, Missouri 63110, USA." } , |
---|
886 | from |
---|
887 | journal { |
---|
888 | title { |
---|
889 | iso-jta "Neuron" , |
---|
890 | ml-jta "Neuron" , |
---|
891 | issn "0896-6273" , |
---|
892 | name "Neuron" } , |
---|
893 | imp { |
---|
894 | date |
---|
895 | std { |
---|
896 | year 1995 , |
---|
897 | month 7 } , |
---|
898 | volume "15" , |
---|
899 | issue "1" , |
---|
900 | pages "115-126" , |
---|
901 | language "eng" , |
---|
902 | pubstatus ppublish , |
---|
903 | history { |
---|
904 | { |
---|
905 | pubstatus pubmed , |
---|
906 | date |
---|
907 | std { |
---|
908 | year 1995 , |
---|
909 | month 7 , |
---|
910 | day 1 } } , |
---|
911 | { |
---|
912 | pubstatus medline , |
---|
913 | date |
---|
914 | std { |
---|
915 | year 1995 , |
---|
916 | month 7 , |
---|
917 | day 1 , |
---|
918 | hour 0 , |
---|
919 | minute 1 } } } } } , |
---|
920 | ids { |
---|
921 | pubmed 7619516 , |
---|
922 | pii "0896-6273(95)90069-1" } } } } , |
---|
923 | pub { |
---|
924 | pub { |
---|
925 | pmid 1741056 , |
---|
926 | article { |
---|
927 | title { |
---|
928 | name "Primary structure of dystrophin-associated glycoproteins |
---|
929 | linking dystrophin to the extracellular matrix." } , |
---|
930 | authors { |
---|
931 | names |
---|
932 | std { |
---|
933 | { |
---|
934 | name |
---|
935 | name { |
---|
936 | last "Ibraghimov-Beskrovnaya" , |
---|
937 | initials "O." } } , |
---|
938 | { |
---|
939 | name |
---|
940 | name { |
---|
941 | last "Ervasti" , |
---|
942 | initials "J.M." } } , |
---|
943 | { |
---|
944 | name |
---|
945 | name { |
---|
946 | last "Leveille" , |
---|
947 | initials "C.J." } } , |
---|
948 | { |
---|
949 | name |
---|
950 | name { |
---|
951 | last "Slaughter" , |
---|
952 | initials "C.A." } } , |
---|
953 | { |
---|
954 | name |
---|
955 | name { |
---|
956 | last "Sernett" , |
---|
957 | initials "S.W." } } , |
---|
958 | { |
---|
959 | name |
---|
960 | name { |
---|
961 | last "Campbell" , |
---|
962 | initials "K.P." } } } , |
---|
963 | affil |
---|
964 | str "Howard Hughes Medical Institute, University of Iowa College |
---|
965 | of Medicine, Iowa City 52242." } , |
---|
966 | from |
---|
967 | journal { |
---|
968 | title { |
---|
969 | iso-jta "Nature" , |
---|
970 | ml-jta "Nature" , |
---|
971 | issn "0028-0836" , |
---|
972 | name "Nature" } , |
---|
973 | imp { |
---|
974 | date |
---|
975 | std { |
---|
976 | year 1992 , |
---|
977 | month 2 , |
---|
978 | day 20 } , |
---|
979 | volume "355" , |
---|
980 | issue "6362" , |
---|
981 | pages "696-702" , |
---|
982 | language "eng" , |
---|
983 | pubstatus ppublish , |
---|
984 | history { |
---|
985 | { |
---|
986 | pubstatus pubmed , |
---|
987 | date |
---|
988 | std { |
---|
989 | year 1992 , |
---|
990 | month 2 , |
---|
991 | day 20 } } , |
---|
992 | { |
---|
993 | pubstatus medline , |
---|
994 | date |
---|
995 | std { |
---|
996 | year 1992 , |
---|
997 | month 2 , |
---|
998 | day 20 , |
---|
999 | hour 0 , |
---|
1000 | minute 1 } } } } } , |
---|
1001 | ids { |
---|
1002 | pubmed 1741056 , |
---|
1003 | doi "10.1038/355696a0" } } } } , |
---|
1004 | pub { |
---|
1005 | pub { |
---|
1006 | pmid 1406935 , |
---|
1007 | article { |
---|
1008 | title { |
---|
1009 | name "Deficiency of the 50K dystrophin-associated glycoprotein in |
---|
1010 | severe childhood autosomal recessive muscular dystrophy." } , |
---|
1011 | authors { |
---|
1012 | names |
---|
1013 | std { |
---|
1014 | { |
---|
1015 | name |
---|
1016 | name { |
---|
1017 | last "Matsumura" , |
---|
1018 | initials "K." } } , |
---|
1019 | { |
---|
1020 | name |
---|
1021 | name { |
---|
1022 | last "Tome" , |
---|
1023 | initials "F.M." } } , |
---|
1024 | { |
---|
1025 | name |
---|
1026 | name { |
---|
1027 | last "Collin" , |
---|
1028 | initials "H." } } , |
---|
1029 | { |
---|
1030 | name |
---|
1031 | name { |
---|
1032 | last "Azibi" , |
---|
1033 | initials "K." } } , |
---|
1034 | { |
---|
1035 | name |
---|
1036 | name { |
---|
1037 | last "Chaouch" , |
---|
1038 | initials "M." } } , |
---|
1039 | { |
---|
1040 | name |
---|
1041 | name { |
---|
1042 | last "Kaplan" , |
---|
1043 | initials "J.C." } } , |
---|
1044 | { |
---|
1045 | name |
---|
1046 | name { |
---|
1047 | last "Fardeau" , |
---|
1048 | initials "M." } } , |
---|
1049 | { |
---|
1050 | name |
---|
1051 | name { |
---|
1052 | last "Campbell" , |
---|
1053 | initials "K.P." } } } , |
---|
1054 | affil |
---|
1055 | str "Howard Hughes Medical Institute, University of Iowa College |
---|
1056 | of Medicine, Iowa City 52242." } , |
---|
1057 | from |
---|
1058 | journal { |
---|
1059 | title { |
---|
1060 | iso-jta "Nature" , |
---|
1061 | ml-jta "Nature" , |
---|
1062 | issn "0028-0836" , |
---|
1063 | name "Nature" } , |
---|
1064 | imp { |
---|
1065 | date |
---|
1066 | std { |
---|
1067 | year 1992 , |
---|
1068 | month 9 , |
---|
1069 | day 24 } , |
---|
1070 | volume "359" , |
---|
1071 | issue "6393" , |
---|
1072 | pages "320-322" , |
---|
1073 | language "eng" , |
---|
1074 | pubstatus ppublish , |
---|
1075 | history { |
---|
1076 | { |
---|
1077 | pubstatus pubmed , |
---|
1078 | date |
---|
1079 | std { |
---|
1080 | year 1992 , |
---|
1081 | month 9 , |
---|
1082 | day 24 } } , |
---|
1083 | { |
---|
1084 | pubstatus medline , |
---|
1085 | date |
---|
1086 | std { |
---|
1087 | year 1992 , |
---|
1088 | month 9 , |
---|
1089 | day 24 , |
---|
1090 | hour 0 , |
---|
1091 | minute 1 } } } } } , |
---|
1092 | ids { |
---|
1093 | pubmed 1406935 , |
---|
1094 | doi "10.1038/359320a0" } } } } , |
---|
1095 | update-date |
---|
1096 | std { |
---|
1097 | year 2008 , |
---|
1098 | month 2 , |
---|
1099 | day 11 } } , |
---|
1100 | seq-set { |
---|
1101 | seq { |
---|
1102 | id { |
---|
1103 | other { |
---|
1104 | accession "NM_004393" , |
---|
1105 | version 2 } , |
---|
1106 | gi 148539834 } , |
---|
1107 | descr { |
---|
1108 | molinfo { |
---|
1109 | biomol mRNA , |
---|
1110 | completeness has-right } , |
---|
1111 | title "Homo sapiens dystroglycan 1 (dystrophin-associated glycoprotein |
---|
1112 | 1) (DAG1), mRNA" , |
---|
1113 | create-date |
---|
1114 | std { |
---|
1115 | year 1999 , |
---|
1116 | month 5 , |
---|
1117 | day 7 } } , |
---|
1118 | inst { |
---|
1119 | repr raw , |
---|
1120 | mol rna , |
---|
1121 | length 5537 , |
---|
1122 | seq-data |
---|
1123 | ncbi2na '2920969A6668494B69966689E967A3E9E411D9BB4A6BE729D696665595F |
---|
1124 | 99D265774595AC6E76660A79A6699D9977CA7E9AE9A69A49F6658355AA269AE9A6D7AA528A2604 |
---|
1125 | 5E59AD7565A67A9DEEE75A8E892BB922AE20549DEA142D1F9F5F1F2421CD87E2407E85EA38A3B7 |
---|
1126 | BA977679E79577AA8A17F75D79DDEEBCE9D2D51E952E05748A7B4A87A80149F8A4D4E474B9DD21 |
---|
1127 | 7518A7BD512EBE93D78E91A7B6DA99D3F62E14F5048FE3E5D4BA2334D0ACD2692A0A29FE537E9E |
---|
1128 | 47A8744894457A2A5D55F8478C2AEE4F13F4B899C469EAA506A251355485D4BBBDD4D8ADC57821 |
---|
1129 | 44B89E4B6B8A125D54857AE2BACD3797B9E68E05EE1EFF86B8FFA396174508E15409028F85D791 |
---|
1130 | 28E689F7482C89F441380F2E5AEB8304873F84EDA5F4E9E95A80E4002BAE883AA57DDD7A09EA79 |
---|
1131 | D5E05204BB9784F4EBB2295794A8A990EDE749FA715EEBABE913650C20955DF54066D68A48D4E7 |
---|
1132 | 115117B4794FA955051A735289553528DB941551375253E75D412214E9D752D2A35EF5EA0151AD |
---|
1133 | 14D68762994F3D015415CA553525C76AED209E9144BD7A523D95063853D7A73BA25C792F9C55D5 |
---|
1134 | 105145082518B351140149065F41E1D4514518764A50508051A115694B956AD14502FD4D148FA0 |
---|
1135 | 1E5D165C76CF6451452E8B956E9A205414995227420533E12AC8E5EAFA45C7F8AE08D5B4847F73 |
---|
1136 | 8538A11451E109E09E15E01E6A24927AEA620B5EAC4BD04904949D3B3A5F56124946EA40462CFD |
---|
1137 | 393944842AA97B69EE8E5F62351B51299550AA32A75E42BD0A50BFBAB85691EBBE0E13510823E5 |
---|
1138 | FAC0807A5F65FE885807B2453457920CD15AA7536EBA0E8504111E57E895E550A248D9EA78965A |
---|
1139 | 3678A38E801769797DD4195C89787F0A5109347B86A77A4BEDA45C4BF357BAC515288B95D22996 |
---|
1140 | 54482E5E12A15E20892E28E3B7179112D3D696EBAD92535E74F9E934F94E379C59082682A427C5 |
---|
1141 | 7E2852945F4D082AAE5CD37F92181E861D42554575D4939474F7928A20A755C5575E2C550522EE |
---|
1142 | 5621475DE0528453A88B119579A8E28D50E65D5C52554595F449153A2A42A756D50813855316B4 |
---|
1143 | 5D7573B545F0564265EAE8A4AB2A4AA5E88613AEFB7BA216BA5E4853E545A89611785C9111E112 |
---|
1144 | A97A109595DDEB5D501540927A221FEA87FFCFFCFFF97049FFAFEF4C883DF67D3FF8E9E9DE0245 |
---|
1145 | 3BA2E8AE8A898A0538381D9292E5A9A557A7779BFE5FC11C1EC7BFFDCF46EEDC9E4A3B04E8012C |
---|
1146 | 1C08F03D0287F482F0AF0BFF1BF0DE7BF1701FB3B30FFEAEACEA83E7F9C00C2754ABBF407C8821 |
---|
1147 | 42A12CFFF340A0C73FFD11C6D07EBE778C55225E3EAA5D5A57A74650B57AE7ABF9DD59EF94AA7A |
---|
1148 | 09E8AADDFA94E84D547D4953B11CBA546142AB7D3F53800A87508A4BAE9EE95507FAE752AEA527 |
---|
1149 | 9FBAA917A8AD02B75144D05CFFBFC57FF7B93EFFFFFD75C0283346BFFE011D2EAA13FEB82390CF |
---|
1150 | FCED3B8E77F5D1F85FA59FED704B512D795615154D5FF77A4752D5297EA5E071E802B7A69EA8A2 |
---|
1151 | E52432F4C30037BC9DD0270FFF1C0BFF3125D03EFF3C00023F00EB8E7C492FEC6277C2EF8F53A0 |
---|
1152 | 7869FE7EFF8F7FD55C7FD70EBF03DE83C47AAF7FE5FFF248135B5B5379377B54E1D2A9951DE7D8 |
---|
1153 | F75D7BA08053FE24E1FF7E3B7826F3FEAC7FF2A28397F6430ECD4F578F8ABABABA1529D5FE4448 |
---|
1154 | 9271F7094CD87BFE48A3FBBB9E5D28AA2A7ACA2AAA22B77B5C79DD48A93F55F997DD512A549577 |
---|
1155 | 55E552D54AAB1DE8B892E55EEAA25EC0E6A74BA147AE1EA74E5D42D22FD5EB954884A2442EA378 |
---|
1156 | 5EB88F3F78E174D000C043D50EF52B8A9FE0297D4049D6D957241D453EA4794E4886E9E9520E97 |
---|
1157 | BE53241E8A63AA4B8120C104904397F92925E755E267A9EB8EB6FA1DEE23A2250DD13D0BBD1414 |
---|
1158 | 78EEFFCFD7DCCE3FC23BBFDE4F7B020133407030092EDFCF10000000000'H , |
---|
1159 | hist { |
---|
1160 | assembly { |
---|
1161 | { |
---|
1162 | type partial , |
---|
1163 | dim 2 , |
---|
1164 | segs |
---|
1165 | denseg { |
---|
1166 | dim 2 , |
---|
1167 | numseg 1 , |
---|
1168 | ids { |
---|
1169 | gi 148539834 , |
---|
1170 | gi 81455866 } , |
---|
1171 | starts { |
---|
1172 | 0 , |
---|
1173 | 0 } , |
---|
1174 | lens { |
---|
1175 | 65 } , |
---|
1176 | strands { |
---|
1177 | plus , |
---|
1178 | plus } } } , |
---|
1179 | { |
---|
1180 | type partial , |
---|
1181 | dim 2 , |
---|
1182 | segs |
---|
1183 | denseg { |
---|
1184 | dim 2 , |
---|
1185 | numseg 1 , |
---|
1186 | ids { |
---|
1187 | gi 148539834 , |
---|
1188 | gi 33877876 } , |
---|
1189 | starts { |
---|
1190 | 65 , |
---|
1191 | 0 } , |
---|
1192 | lens { |
---|
1193 | 2608 } , |
---|
1194 | strands { |
---|
1195 | plus , |
---|
1196 | plus } } } , |
---|
1197 | { |
---|
1198 | type partial , |
---|
1199 | dim 2 , |
---|
1200 | segs |
---|
1201 | denseg { |
---|
1202 | dim 2 , |
---|
1203 | numseg 1 , |
---|
1204 | ids { |
---|
1205 | gi 148539834 , |
---|
1206 | gi 398025 } , |
---|
1207 | starts { |
---|
1208 | 2673 , |
---|
1209 | 2649 } , |
---|
1210 | lens { |
---|
1211 | 1 } , |
---|
1212 | strands { |
---|
1213 | plus , |
---|
1214 | plus } } } , |
---|
1215 | { |
---|
1216 | type partial , |
---|
1217 | dim 2 , |
---|
1218 | segs |
---|
1219 | denseg { |
---|
1220 | dim 2 , |
---|
1221 | numseg 1 , |
---|
1222 | ids { |
---|
1223 | gi 148539834 , |
---|
1224 | gi 33877876 } , |
---|
1225 | starts { |
---|
1226 | 2674 , |
---|
1227 | 2609 } , |
---|
1228 | lens { |
---|
1229 | 1708 } , |
---|
1230 | strands { |
---|
1231 | plus , |
---|
1232 | plus } } } , |
---|
1233 | { |
---|
1234 | type partial , |
---|
1235 | dim 2 , |
---|
1236 | segs |
---|
1237 | denseg { |
---|
1238 | dim 2 , |
---|
1239 | numseg 1 , |
---|
1240 | ids { |
---|
1241 | gi 148539834 , |
---|
1242 | gi 58554642 } , |
---|
1243 | starts { |
---|
1244 | 4382 , |
---|
1245 | 97 } , |
---|
1246 | lens { |
---|
1247 | 491 } , |
---|
1248 | strands { |
---|
1249 | plus , |
---|
1250 | plus } } } , |
---|
1251 | { |
---|
1252 | type partial , |
---|
1253 | dim 2 , |
---|
1254 | segs |
---|
1255 | denseg { |
---|
1256 | dim 2 , |
---|
1257 | numseg 1 , |
---|
1258 | ids { |
---|
1259 | gi 148539834 , |
---|
1260 | gi 46844012 } , |
---|
1261 | starts { |
---|
1262 | 4873 , |
---|
1263 | 199 } , |
---|
1264 | lens { |
---|
1265 | 494 } , |
---|
1266 | strands { |
---|
1267 | plus , |
---|
1268 | plus } } } , |
---|
1269 | { |
---|
1270 | type partial , |
---|
1271 | dim 2 , |
---|
1272 | segs |
---|
1273 | denseg { |
---|
1274 | dim 2 , |
---|
1275 | numseg 1 , |
---|
1276 | ids { |
---|
1277 | gi 148539834 , |
---|
1278 | gi 11547519 } , |
---|
1279 | starts { |
---|
1280 | 5367 , |
---|
1281 | 0 } , |
---|
1282 | lens { |
---|
1283 | 152 } , |
---|
1284 | strands { |
---|
1285 | plus , |
---|
1286 | minus } } } , |
---|
1287 | { |
---|
1288 | type partial , |
---|
1289 | dim 2 , |
---|
1290 | segs |
---|
1291 | denseg { |
---|
1292 | dim 2 , |
---|
1293 | numseg 1 , |
---|
1294 | ids { |
---|
1295 | gi 148539834 , |
---|
1296 | gi 6503484 } , |
---|
1297 | starts { |
---|
1298 | 5519 , |
---|
1299 | 0 } , |
---|
1300 | lens { |
---|
1301 | 18 } , |
---|
1302 | strands { |
---|
1303 | plus , |
---|
1304 | minus } } } } , |
---|
1305 | replaces { |
---|
1306 | date |
---|
1307 | std { |
---|
1308 | year 2007 , |
---|
1309 | month 6 , |
---|
1310 | day 2 } , |
---|
1311 | ids { |
---|
1312 | gi 4758115 } } } } , |
---|
1313 | annot { |
---|
1314 | { |
---|
1315 | data |
---|
1316 | ftable { |
---|
1317 | { |
---|
1318 | data |
---|
1319 | imp { |
---|
1320 | key "polyA_signal" } , |
---|
1321 | location |
---|
1322 | int { |
---|
1323 | from 4347 , |
---|
1324 | to 4352 , |
---|
1325 | strand plus , |
---|
1326 | id |
---|
1327 | gi 148539834 } } , |
---|
1328 | { |
---|
1329 | data |
---|
1330 | imp { |
---|
1331 | key "polyA_site" } , |
---|
1332 | location |
---|
1333 | pnt { |
---|
1334 | point 4387 , |
---|
1335 | strand plus , |
---|
1336 | id |
---|
1337 | gi 148539834 } } , |
---|
1338 | { |
---|
1339 | data |
---|
1340 | imp { |
---|
1341 | key "polyA_signal" } , |
---|
1342 | location |
---|
1343 | int { |
---|
1344 | from 5497 , |
---|
1345 | to 5502 , |
---|
1346 | strand plus , |
---|
1347 | id |
---|
1348 | gi 148539834 } } , |
---|
1349 | { |
---|
1350 | data |
---|
1351 | imp { |
---|
1352 | key "polyA_site" } , |
---|
1353 | location |
---|
1354 | pnt { |
---|
1355 | point 5521 , |
---|
1356 | strand plus , |
---|
1357 | id |
---|
1358 | gi 148539834 } } , |
---|
1359 | { |
---|
1360 | data |
---|
1361 | gene { |
---|
1362 | locus "DAG1" , |
---|
1363 | desc "dystroglycan 1 (dystrophin-associated glycoprotein |
---|
1364 | 1)" , |
---|
1365 | syn { |
---|
1366 | "A3a" , |
---|
1367 | "DAG" , |
---|
1368 | "AGRNR" , |
---|
1369 | "156DAG" } } , |
---|
1370 | location |
---|
1371 | int { |
---|
1372 | from 0 , |
---|
1373 | to 5536 , |
---|
1374 | strand plus , |
---|
1375 | id |
---|
1376 | gi 148539834 } , |
---|
1377 | dbxref { |
---|
1378 | { |
---|
1379 | db "GeneID" , |
---|
1380 | tag |
---|
1381 | id 1605 } , |
---|
1382 | { |
---|
1383 | db "HGNC" , |
---|
1384 | tag |
---|
1385 | id 2666 } , |
---|
1386 | { |
---|
1387 | db "HPRD" , |
---|
1388 | tag |
---|
1389 | str "HPRD_00546" } , |
---|
1390 | { |
---|
1391 | db "MIM" , |
---|
1392 | tag |
---|
1393 | id 128239 } } } } } , |
---|
1394 | { |
---|
1395 | db other , |
---|
1396 | name "Annot:STS" , |
---|
1397 | data |
---|
1398 | ftable { |
---|
1399 | { |
---|
1400 | data |
---|
1401 | imp { |
---|
1402 | key "STS" } , |
---|
1403 | location |
---|
1404 | int { |
---|
1405 | from 1789 , |
---|
1406 | to 2667 , |
---|
1407 | strand plus , |
---|
1408 | id |
---|
1409 | gi 148539834 } , |
---|
1410 | qual { |
---|
1411 | { |
---|
1412 | qual "standard_name" , |
---|
1413 | val "PMC28400P1" } } , |
---|
1414 | dbxref { |
---|
1415 | { |
---|
1416 | db "UniSTS" , |
---|
1417 | tag |
---|
1418 | id 272410 } } } , |
---|
1419 | { |
---|
1420 | data |
---|
1421 | imp { |
---|
1422 | key "STS" } , |
---|
1423 | location |
---|
1424 | int { |
---|
1425 | from 3429 , |
---|
1426 | to 3771 , |
---|
1427 | strand plus , |
---|
1428 | id |
---|
1429 | gi 148539834 } , |
---|
1430 | qual { |
---|
1431 | { |
---|
1432 | qual "standard_name" , |
---|
1433 | val "D3S3337" } } , |
---|
1434 | dbxref { |
---|
1435 | { |
---|
1436 | db "UniSTS" , |
---|
1437 | tag |
---|
1438 | id 5975 } } } , |
---|
1439 | { |
---|
1440 | data |
---|
1441 | imp { |
---|
1442 | key "STS" } , |
---|
1443 | location |
---|
1444 | int { |
---|
1445 | from 2630 , |
---|
1446 | to 2791 , |
---|
1447 | strand plus , |
---|
1448 | id |
---|
1449 | gi 148539834 } , |
---|
1450 | qual { |
---|
1451 | { |
---|
1452 | qual "standard_name" , |
---|
1453 | val "GDB:215839" } } , |
---|
1454 | dbxref { |
---|
1455 | { |
---|
1456 | db "UniSTS" , |
---|
1457 | tag |
---|
1458 | id 156205 } } } , |
---|
1459 | { |
---|
1460 | data |
---|
1461 | imp { |
---|
1462 | key "STS" } , |
---|
1463 | location |
---|
1464 | int { |
---|
1465 | from 4139 , |
---|
1466 | to 4265 , |
---|
1467 | strand plus , |
---|
1468 | id |
---|
1469 | gi 148539834 } , |
---|
1470 | qual { |
---|
1471 | { |
---|
1472 | qual "standard_name" , |
---|
1473 | val "Bdy62f05" } } , |
---|
1474 | dbxref { |
---|
1475 | { |
---|
1476 | db "UniSTS" , |
---|
1477 | tag |
---|
1478 | id 36695 } } } , |
---|
1479 | { |
---|
1480 | data |
---|
1481 | imp { |
---|
1482 | key "STS" } , |
---|
1483 | location |
---|
1484 | int { |
---|
1485 | from 4553 , |
---|
1486 | to 4707 , |
---|
1487 | strand plus , |
---|
1488 | id |
---|
1489 | gi 148539834 } , |
---|
1490 | qual { |
---|
1491 | { |
---|
1492 | qual "standard_name" , |
---|
1493 | val "G54125" } } , |
---|
1494 | dbxref { |
---|
1495 | { |
---|
1496 | db "UniSTS" , |
---|
1497 | tag |
---|
1498 | id 109362 } } } } } , |
---|
1499 | { |
---|
1500 | db other , |
---|
1501 | name "Annot:Exon" , |
---|
1502 | desc { |
---|
1503 | title "NM exons based on Splign alignments" } , |
---|
1504 | data |
---|
1505 | ftable { |
---|
1506 | { |
---|
1507 | data |
---|
1508 | imp { |
---|
1509 | key "exon" } , |
---|
1510 | location |
---|
1511 | int { |
---|
1512 | from 0 , |
---|
1513 | to 301 , |
---|
1514 | strand plus , |
---|
1515 | id |
---|
1516 | gi 148539834 } , |
---|
1517 | qual { |
---|
1518 | { |
---|
1519 | qual "number" , |
---|
1520 | val "1" } , |
---|
1521 | { |
---|
1522 | qual "inference" , |
---|
1523 | val "alignment:Splign" } } } , |
---|
1524 | { |
---|
1525 | data |
---|
1526 | imp { |
---|
1527 | key "exon" } , |
---|
1528 | location |
---|
1529 | int { |
---|
1530 | from 302 , |
---|
1531 | to 702 , |
---|
1532 | strand plus , |
---|
1533 | id |
---|
1534 | gi 148539834 } , |
---|
1535 | qual { |
---|
1536 | { |
---|
1537 | qual "number" , |
---|
1538 | val "2" } , |
---|
1539 | { |
---|
1540 | qual "inference" , |
---|
1541 | val "alignment:Splign" } } } , |
---|
1542 | { |
---|
1543 | data |
---|
1544 | imp { |
---|
1545 | key "exon" } , |
---|
1546 | location |
---|
1547 | int { |
---|
1548 | from 703 , |
---|
1549 | to 5521 , |
---|
1550 | strand plus , |
---|
1551 | id |
---|
1552 | gi 148539834 } , |
---|
1553 | qual { |
---|
1554 | { |
---|
1555 | qual "number" , |
---|
1556 | val "3" } , |
---|
1557 | { |
---|
1558 | qual "inference" , |
---|
1559 | val "alignment:Splign" } } } } } } } , |
---|
1560 | seq { |
---|
1561 | id { |
---|
1562 | other { |
---|
1563 | accession "NP_004384" , |
---|
1564 | version 2 } , |
---|
1565 | gi 148539835 } , |
---|
1566 | descr { |
---|
1567 | molinfo { |
---|
1568 | biomol peptide } , |
---|
1569 | title "dystroglycan 1 preproprotein [Homo sapiens]" , |
---|
1570 | create-date |
---|
1571 | std { |
---|
1572 | year 1999 , |
---|
1573 | month 5 , |
---|
1574 | day 7 } } , |
---|
1575 | inst { |
---|
1576 | repr raw , |
---|
1577 | mol aa , |
---|
1578 | length 895 , |
---|
1579 | seq-data |
---|
1580 | ncbieaa "MRMSVGLSLLLPLWGRTFLLLLSVVMAQSHWPSEPSEAVRDWENQLEASMHSVLSDLHE |
---|
1581 | AVPTVVGIPDGTAVVGRSFRVTIPTDLIASSGDIIKVSAAGKEALPSWLHWDSQSHTLEGLPLDTDKGVHYISVSATR |
---|
1582 | LGANGSHIPQTSSVFSIEVYPEDHSELQSVRTASPDPGEVVSSACAADEPVTVLTVILDADLTKMTPKQRIDLLHRMR |
---|
1583 | SFSEVELHNMKLVPVVNNRLFDMSAFMAGPGNAKKVVENGALLSWKLGCSLNQNSVPDIHGVEAPAREGAMSAQLGYP |
---|
1584 | VVGWHIANKKPPLPKRVRRQIHATPTPVTAIGPPTTAIQEPPSRIVPTPTSPAIAPPTETMAPPVRDPVPGKPTVTIR |
---|
1585 | TRGAIIQTPTLGPIQPTRVSEAGTTVPGQIRPTMTIPGYVEPTAVATPPTTTTKKPRVSTPKPATPSTDSTTTTTRRP |
---|
1586 | TKKPRTPRPVPRVTTKVSITRLETASPPTRIRTTTSGVPRGGEPNQRPELKNHIDRVDAWVGTYFEVKIPSDTFYDHE |
---|
1587 | DTTTDKLKLTLKLREQQLVGEKSWVQFNSNSQLMYGLPDSSHVGKHEYFMHATDKGGLSAVDAFEIHVHRRPQGDRAP |
---|
1588 | ARFKAKFVGDPALVLNDIHKKIALVKKLAFAFGDRNCSTITLQNITRGSIVVEWTNNTLPLEPCPKEQIAGLSRRIAE |
---|
1589 | DDGKPRPAFSNALEPDFKATSITVTGSGSCRHLQFIPVVPPRRVPSEAPPTEVPDRDPEKSSEDDVYLHTVIPAVVVA |
---|
1590 | AILLIAGIIAMICYRKKRKGKLTLEDQATFIKKGVPIIFADELDDSKPPPSSSMPLILQEEKAPLPPPEYPNQSVPET |
---|
1591 | TPLNQDTMGEYTPLRDEDPNAPPYQPPPPFTAPMEGKGSRPKNMTPYRSPPPYVPP" , |
---|
1592 | hist { |
---|
1593 | replaces { |
---|
1594 | date |
---|
1595 | std { |
---|
1596 | year 2007 , |
---|
1597 | month 6 , |
---|
1598 | day 2 } , |
---|
1599 | ids { |
---|
1600 | gi 4758116 } } } } , |
---|
1601 | annot { |
---|
1602 | { |
---|
1603 | data |
---|
1604 | ftable { |
---|
1605 | { |
---|
1606 | data |
---|
1607 | prot { |
---|
1608 | processed signal-peptide } , |
---|
1609 | location |
---|
1610 | int { |
---|
1611 | from 0 , |
---|
1612 | to 28 , |
---|
1613 | id |
---|
1614 | gi 148539835 } } , |
---|
1615 | { |
---|
1616 | data |
---|
1617 | prot { |
---|
1618 | name { |
---|
1619 | "dystroglycan 1 proprotein" } , |
---|
1620 | processed preprotein } , |
---|
1621 | location |
---|
1622 | int { |
---|
1623 | from 29 , |
---|
1624 | to 894 , |
---|
1625 | id |
---|
1626 | gi 148539835 } } , |
---|
1627 | { |
---|
1628 | data |
---|
1629 | prot { |
---|
1630 | name { |
---|
1631 | "alpha-dystroglycan" } , |
---|
1632 | processed mature } , |
---|
1633 | location |
---|
1634 | int { |
---|
1635 | from 29 , |
---|
1636 | to 652 , |
---|
1637 | id |
---|
1638 | gi 148539835 } } , |
---|
1639 | { |
---|
1640 | data |
---|
1641 | prot { |
---|
1642 | name { |
---|
1643 | "beta-dystroglycan" } , |
---|
1644 | processed mature } , |
---|
1645 | location |
---|
1646 | int { |
---|
1647 | from 653 , |
---|
1648 | to 894 , |
---|
1649 | id |
---|
1650 | gi 148539835 } } , |
---|
1651 | { |
---|
1652 | data |
---|
1653 | prot { |
---|
1654 | name { |
---|
1655 | "dystroglycan 1 preproprotein" , |
---|
1656 | "alpha-dystroglycan" , |
---|
1657 | "dystrophin-associated glycoprotein-1" , |
---|
1658 | "beta-dystroglycan" } } , |
---|
1659 | location |
---|
1660 | int { |
---|
1661 | from 0 , |
---|
1662 | to 894 , |
---|
1663 | id |
---|
1664 | gi 148539835 } } } } , |
---|
1665 | { |
---|
1666 | db other , |
---|
1667 | name "Annot:CDD" , |
---|
1668 | desc { |
---|
1669 | name "CDDSearch" , |
---|
1670 | create-date |
---|
1671 | std { |
---|
1672 | year 2007 , |
---|
1673 | month 6 , |
---|
1674 | day 5 , |
---|
1675 | hour 13 , |
---|
1676 | minute 47 , |
---|
1677 | second 25 } } , |
---|
1678 | data |
---|
1679 | ftable { |
---|
1680 | { |
---|
1681 | data |
---|
1682 | region "CADG" , |
---|
1683 | comment "Dystroglycan-type cadherin-like domains. |
---|
1684 | Cadherin-homologous domains present in metazoan dystroglycans and |
---|
1685 | alpha/epsilon sarcoglycans, yeast Axl2p and in a very large protein from |
---|
1686 | magnetotactic bacteria. Likely to bind calcium ions." , |
---|
1687 | location |
---|
1688 | int { |
---|
1689 | from 498 , |
---|
1690 | to 598 , |
---|
1691 | id |
---|
1692 | gi 148539835 } , |
---|
1693 | ext { |
---|
1694 | type |
---|
1695 | str "cddScoreData" , |
---|
1696 | data { |
---|
1697 | { |
---|
1698 | label |
---|
1699 | str "definition" , |
---|
1700 | data |
---|
1701 | str "smart00736" } , |
---|
1702 | { |
---|
1703 | label |
---|
1704 | str "short_name" , |
---|
1705 | data |
---|
1706 | str "CADG" } , |
---|
1707 | { |
---|
1708 | label |
---|
1709 | str "score" , |
---|
1710 | data |
---|
1711 | int 188 } , |
---|
1712 | { |
---|
1713 | label |
---|
1714 | str "evalue" , |
---|
1715 | data |
---|
1716 | real { 164132, 10, -19 } } , |
---|
1717 | { |
---|
1718 | label |
---|
1719 | str "bit_score" , |
---|
1720 | data |
---|
1721 | real { 765172, 10, -4 } } } } , |
---|
1722 | dbxref { |
---|
1723 | { |
---|
1724 | db "CDD" , |
---|
1725 | tag |
---|
1726 | id 48003 } } } , |
---|
1727 | { |
---|
1728 | data |
---|
1729 | region "CADG" , |
---|
1730 | comment "Dystroglycan-type cadherin-like domains. |
---|
1731 | Cadherin-homologous domains present in metazoan dystroglycans and |
---|
1732 | alpha/epsilon sarcoglycans, yeast Axl2p and in a very large protein from |
---|
1733 | magnetotactic bacteria. Likely to bind calcium ions." , |
---|
1734 | location |
---|
1735 | int { |
---|
1736 | from 63 , |
---|
1737 | to 161 , |
---|
1738 | id |
---|
1739 | gi 148539835 } , |
---|
1740 | ext { |
---|
1741 | type |
---|
1742 | str "cddScoreData" , |
---|
1743 | data { |
---|
1744 | { |
---|
1745 | label |
---|
1746 | str "definition" , |
---|
1747 | data |
---|
1748 | str "smart00736" } , |
---|
1749 | { |
---|
1750 | label |
---|
1751 | str "short_name" , |
---|
1752 | data |
---|
1753 | str "CADG" } , |
---|
1754 | { |
---|
1755 | label |
---|
1756 | str "score" , |
---|
1757 | data |
---|
1758 | int 177 } , |
---|
1759 | { |
---|
1760 | label |
---|
1761 | str "evalue" , |
---|
1762 | data |
---|
1763 | real { 285713, 10, -18 } } , |
---|
1764 | { |
---|
1765 | label |
---|
1766 | str "bit_score" , |
---|
1767 | data |
---|
1768 | real { 7228, 10, -2 } } } } , |
---|
1769 | dbxref { |
---|
1770 | { |
---|
1771 | db "CDD" , |
---|
1772 | tag |
---|
1773 | id 48003 } } } , |
---|
1774 | { |
---|
1775 | data |
---|
1776 | region "DAG1" , |
---|
1777 | partial TRUE , |
---|
1778 | comment "Dystroglycan (Dystrophin-associated glycoprotein 1). |
---|
1779 | Dystroglycan is one of the dystrophin-associated glycoproteins, which is |
---|
1780 | encoded by a 5.5 kb transcript in human." , |
---|
1781 | location |
---|
1782 | int { |
---|
1783 | from 467 , |
---|
1784 | to 883 , |
---|
1785 | id |
---|
1786 | gi 148539835 , |
---|
1787 | fuzz-from |
---|
1788 | lim lt } , |
---|
1789 | ext { |
---|
1790 | type |
---|
1791 | str "cddScoreData" , |
---|
1792 | data { |
---|
1793 | { |
---|
1794 | label |
---|
1795 | str "definition" , |
---|
1796 | data |
---|
1797 | str "pfam05454" } , |
---|
1798 | { |
---|
1799 | label |
---|
1800 | str "short_name" , |
---|
1801 | data |
---|
1802 | str "DAG1" } , |
---|
1803 | { |
---|
1804 | label |
---|
1805 | str "score" , |
---|
1806 | data |
---|
1807 | int 1364 } , |
---|
1808 | { |
---|
1809 | label |
---|
1810 | str "evalue" , |
---|
1811 | data |
---|
1812 | real { 643304, 10, -156 } } , |
---|
1813 | { |
---|
1814 | label |
---|
1815 | str "bit_score" , |
---|
1816 | data |
---|
1817 | real { 52977, 10, -2 } } } } , |
---|
1818 | dbxref { |
---|
1819 | { |
---|
1820 | db "CDD" , |
---|
1821 | tag |
---|
1822 | id 69003 } } } , |
---|
1823 | { |
---|
1824 | data |
---|
1825 | region "DAG1" , |
---|
1826 | partial TRUE , |
---|
1827 | comment "Dystroglycan (Dystrophin-associated glycoprotein 1). |
---|
1828 | Dystroglycan is one of the dystrophin-associated glycoproteins, which is |
---|
1829 | encoded by a 5.5 kb transcript in human." , |
---|
1830 | location |
---|
1831 | int { |
---|
1832 | from 41 , |
---|
1833 | to 411 , |
---|
1834 | id |
---|
1835 | gi 148539835 , |
---|
1836 | fuzz-to |
---|
1837 | lim gt } , |
---|
1838 | ext { |
---|
1839 | type |
---|
1840 | str "cddScoreData" , |
---|
1841 | data { |
---|
1842 | { |
---|
1843 | label |
---|
1844 | str "definition" , |
---|
1845 | data |
---|
1846 | str "pfam05454" } , |
---|
1847 | { |
---|
1848 | label |
---|
1849 | str "short_name" , |
---|
1850 | data |
---|
1851 | str "DAG1" } , |
---|
1852 | { |
---|
1853 | label |
---|
1854 | str "score" , |
---|
1855 | data |
---|
1856 | int 1303 } , |
---|
1857 | { |
---|
1858 | label |
---|
1859 | str "evalue" , |
---|
1860 | data |
---|
1861 | real { 62179, 10, -148 } } , |
---|
1862 | { |
---|
1863 | label |
---|
1864 | str "bit_score" , |
---|
1865 | data |
---|
1866 | real { 506273, 10, -3 } } } } , |
---|
1867 | dbxref { |
---|
1868 | { |
---|
1869 | db "CDD" , |
---|
1870 | tag |
---|
1871 | id 69003 } } } } } } } } , |
---|
1872 | annot { |
---|
1873 | { |
---|
1874 | data |
---|
1875 | ftable { |
---|
1876 | { |
---|
1877 | data |
---|
1878 | cdregion { |
---|
1879 | code { |
---|
1880 | id 1 } } , |
---|
1881 | product |
---|
1882 | whole |
---|
1883 | gi 148539835 , |
---|
1884 | location |
---|
1885 | int { |
---|
1886 | from 418 , |
---|
1887 | to 3105 , |
---|
1888 | strand plus , |
---|
1889 | id |
---|
1890 | gi 148539834 } , |
---|
1891 | dbxref { |
---|
1892 | { |
---|
1893 | db "CCDS" , |
---|
1894 | tag |
---|
1895 | str "CCDS2799.1" } } } } } } } |
---|
1896 | |
---|